Bioinformatics Tools and Blogs
Tools, Blogs
recent posts
- A Guide to Slurm Memory Management for Bioinformatics
- Omics Workflow Suite
- An Architectural Guide for Integrating a NextSeq 2000 with On-Premises NAS and HPC
- Recovering Undetermined Reads: The Local Demultiplexer Pipeline
- Cell Proportion Estimation and Adjustment Methods — Companion Tutorial
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This tutorial outlines methods for adjusting cell proportions using DNA methylation data from peripheral blood. Techniques discussed include RefFreeEWAS and Surrogate Variable Analysis (SVA), which don’t require external datasets, as well as Houseman et al., which does. It provides R code samples for implementing these methodologies.
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Epigenetics is a dynamic field exploring gene expression regulation without altering DNA sequences through mechanisms like DNA methylation and histone modifications. This research involves sophisticated data analysis methods and bioinformatics tools to understand epigenetic changes, with promising applications in personalized medicine, disease treatment, and insights into aging and environmental influences on health.
Bioinformatics Tools and Blogs 